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Clarinex (desloratadine) is a good option for once-daily allergy relief. It doesn't make you feel sleepy, but you need a prescription. Claritin (loratadine) is a once-daily medicine for allergies that won't make you as sleepy as other medicines that work like it.

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Desloratadine (trade name Clarinex in the US and Aerius in Europe and Canada) is a tricyclic H 1-antihistamine that is used to treat allergies.

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Claritin vs Zyrtec comparison. Over-the-counter allergy relief medications Claritin-D is Claritin with pseudoephedrine that comes in 12-hour and 24-hour doses.

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